Charles River Laboratories Scientist in Saffron Walden, United Kingdom


Req ID: 36140

Location: Saffron Walden, ESS, GB, cb10 1xl

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

We have an exciting opportunitiy for a self-motivated scientist at our laboratories in Chesterford Park, around 10 miles from Cambridge.

You will be a self-motivated and enthusiastic about working in the lab and have experience with plate-based screening and assay development, ideally gained within industry or an academic screening environment.

You will be working on a range of biochemical and cellular assay formats, solving challenging problems, analysing and reporting data to advance client projects aimed at discovering new medicines.

This role will place you as part of a cross-functional team working at the forefront of drug discovery, interacting with other groups within the organisation including computational chemistry, chemistry, compound handling and in vitro and in vivo DMPK.

You will work in a challenging and dynamic environment that provides the ideal opportunity to showcase your expertise in contributing to the discovery of potential new medicines. You will also be given the chance to develop your own skills via interaction with scientists from diverse cultural and scientific backgrounds.

Our ideal candidate will have a degree level qualification, between 1 and 3 years’ relevant experience, and a passion for applying scientific expertise to drug discovery collaborations. Adept in working as part of a multi-disciplinary team, you will need to possess the flexibility required to work in a goal-oriented environment, as well as:

  • Experience in developing, optimizing and executing in vitro biological assays (biochemical, cell based) for HTS small molecule drug discovery projects.

  • The ability to QC equipment and data and use this experience to troubleshoot HTS assays

  • A pro-active and positive problem solving mindset

  • Suggesting new ideas or initiatives that impact upon project progress

  • An awareness of the relevant scientific literature and contemporary laboratory practices

  • An ability to work to tight deadlines

  • Demonstrating strong organizational skills

  • A desire to work in cross-functional teams where your data will have a direct impact on project goals

  • A willingness to interact with other members of the department, sharing assay development and screening best practises

  • Presenting your own work confidently to both internal project teams and in client meetings

  • An ability to work in a safe manner at all times ensuring procedures/SOPs are adhered to

About Discovery

Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 70% of the drugs approved by the FDA in 2016.

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